C-C Motif Chemokine 21 (CCL21) Antibody

CCL21 Antibody is a Rabbit Polyclonal antibody against CCL21. This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Target	C-C Motif Chemokine 21 (CCL21)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	IHC
Host	Rabbit
Recommended dilutions	IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 24-134 of human CCL21.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00585 (UniProt, ExPASy)
UniProt Secondary AC	Q6ICR7
Gene Symbol	CCL21
GeneID	6366
OMIM	602737
NCBI Accession	NP_002980.1
HGNC	10620
KEGG	hsa:6366
String	9606.ENSP00000259607
Molecular Weight	Calculated MW: 15 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on C-C Motif Chemokine 21 (CCL21)

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