Cyclin B2 (CCNB2) Antibody

CCNB2 Antibody is a Rabbit Polyclonal antibody against CCNB2. Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

Target	Cyclin B2 (CCNB2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Cyclin B2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95067 (UniProt, ExPASy)
UniProt Secondary AC	B3KM93, Q6FI99
UniProt Entry Name	CCNB2_HUMAN
Gene Symbol	CCNB2
GeneID	9133
NCBI Accession	NP_004692.1
KEGG	hsa:9133
String	9606.ENSP00000288207
Molecular Weight	Calculated MW: 45 kDa Observed MW: 45 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cyclin B2 (CCNB2)

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