G1/S-Specific Cyclin-D2 (CCND2) Antibody

Catalogue No: abx001471
Price: £120.00
(Size: 20 µl)
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G1/S-Specific Cyclin-D2 (CCND2) Antibody G1/S-Specific Cyclin-D2 (CCND2) Antibody G1/S-Specific Cyclin-D2 (CCND2) Antibody

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CCND2 Antibody is a Rabbit Polyclonal antibody against CCND2. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.

Target G1/S-Specific Cyclin-D2 (CCND2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CCND2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P30279 (UniProt, ExPASy)
UniProt Secondary AC A8K531, Q13955, Q5U035
UniProt Entry Name CCND2_HUMAN
Gene Symbol CCND2
GeneID 894
KEGG hsa:894
String 9606.ENSP00000261254
Molecular Weight Calculated MW: 24 kDa, 33 kDa
Observed MW: 37 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on G1/S-Specific Cyclin-D2 (CCND2) Antibody

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