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Cyclin D3 (CCND3) Antibody

Catalogue No: abx001007
Price: £120.00
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CCND3 Antibody is a Rabbit Polyclonal antibody against CCND3. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.

Target CCND3
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CCND3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P30281 (UniProt, ExPASy)
UniProt Secondary AC B2RD63, B3KQ22, E9PAS4, E9PB36, Q5T8J0, Q6FG62, Q96F49
UniProt Entry Name CCND3_HUMAN
Gene Symbol CCND3
GeneID 896
String 9606.ENSP00000362082
Molecular Weight Calculated MW: 9 kDa, 22 kDa, 24 kDa, 32 kDa
Observed MW: 33 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cyclin D3 (CCND3) Antibody

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