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Cyclin-H (CCNH) Antibody

Catalogue No: abx000948
Price: £120.00
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Cyclin-H (CCNH) Antibody

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CCNH Antibody is a Rabbit Polyclonal antibody against CCNH. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.

Target CCNH
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CCNH.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P51946 (UniProt, ExPASy)
UniProt Secondary AC Q53X72, Q8TBL9
UniProt Entry Name CCNH_HUMAN
Gene Symbol CCNH
GeneID 902
String 9606.ENSP00000256897
Molecular Weight Calculated MW: 37 kDa
Observed MW: 36 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cyclin-H (CCNH) Antibody

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