Syndecan 1 (SDC1) Antibody

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. This antibody is supplied as crude ascites.

Target	Syndecan 1 (SDC1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IF/ICC, FCM
Host	Mouse
Recommended dilutions	WB: 1/500 - 1/8000, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 210-238 amino acids from the C-terminal region of human CD138.
Isotype	IgM
Form	Liquid
Purification	Unpurified crude ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P18827 (UniProt, ExPASy)
UniProt Secondary AC	D6W523, Q53QV0, Q546D3, Q96HB7
UniProt Entry Name	SDC1_HUMAN
KEGG	hsa:6382
String	9606.ENSP00000370542
Molecular Weight	Calculated MW: 32.5 kDa
Buffer	Ascites containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Syndecan 1 (SDC1)

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