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Syndecan 1 (SDC1) Antibody
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Catalogue No: abx025508
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US$623.50
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. This antibody is supplied as crude ascites.
Research Articles on Syndecan 1 (SDC1)
| Target | Syndecan 1 (SDC1) |
| Research Area | Tumor Immunity, Infection Immunity, Immunodeficiency, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/8000, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 210-238 amino acids from the C-terminal region of human CD138. |
| Isotype | IgM |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P18827 (UniProt, ExPASy) |
| UniProt Secondary AC | D6W523, Q53QV0, Q546D3, Q96HB7 |
| UniProt Entry Name | SDC1_HUMAN |
| KEGG | hsa:6382 |
| String | 9606.ENSP00000370542 |
| Molecular Weight | Calculated MW: 32.5 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |