C-type Lectin Domain Family 4 Member K (CD207) Antibody
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Catalogue No: abx005029
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US$217.50
(Size: 20 µl)
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Datasheet SDS
CD207 Antibody is a Rabbit Polyclonal antibody against CD207. The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Research Articles on C-type Lectin Domain Family 4 Member K (CD207)
| Target | C-type Lectin Domain Family 4 Member K (CD207) |
| Research Area | Cellular Differentiation and Adhesion, Infection Immunity, Dermatology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to CD207. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9UJ71 (UniProt, ExPASy) |
| UniProt Entry Name | CLC4K_HUMAN |
| Gene Symbol | CD207 |
| GeneID | 50489 |
| NCBI Accession | NP_056532.4 |
| String | 9606.ENSP00000386378 |
| Molecular Weight | Calculated MW: 37 kDa Observed MW: 40-50 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |