T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex.The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.Low expression of the antigen results in impaired immune response.Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Target	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC, IF/ICC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CD247 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P20963 (UniProt, ExPASy)
UniProt Secondary AC	B1AK49, Q5VX13, Q8TAX4
Gene Symbol	CD247
GeneID	919
OMIM	186780
HGNC	1677
Ensembl	ENSG00000198821
Molecular Weight	18 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247)

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