T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody

CD247 Antibody is a Rabbit Polyclonal antibody against CD247. The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Target	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 50-164 of human CD3H.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P20963 (UniProt, ExPASy)
UniProt Secondary AC	B1AK49, Q5VX13, Q8TAX4
Gene Symbol	CD247
GeneID	919
NCBI Accession	NP_932170.1
Molecular Weight	Calculated MW: 19 kDa Observed MW: 19 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247)

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