+44 (0) 1223 755950
+1 832 327 7413
Orders to United States ship from United States
| Target | Programmed Cell Death 1 Ligand 1 (CD274) |
| Research Area | Signal Transduction, Tumor Immunity, Infection Immunity, Immunology, Autoimmunity, Cancer |
| Clonality | Monoclonal |
| Clone | E456 |
| Reactivity | Human, Monkey |
| Tested Applications | FCM |
| Host | Mouse |
| Recommended dilutions | FCM: 10 µl/100 µl of whole blood or 106 cells. Tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | PE |
| Excitation/Emission | 565/575 |
| Laser Line | 550 |
| Immunogen | Full length Human CD274. |
| Isotype | IgG2b Kappa |
| Form | Liquid |
| Storage | Store in the dark at 2°C to 8°C. Avoid exposure to light. Do not freeze. |
| Shelf Life | The shelf life is at least 12 months. |
| UniProt Primary AC | Q9NZQ7 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RBA2, B4DU27, Q14CJ2, Q2V8D5, Q66RK1, Q6WEX4, Q9NUZ5 |
| UniProt Entry Name | PD1L1_HUMAN |
| Gene Symbol | CD274 |
| GeneID | 29126 |
| OMIM | 605402 |
| HGNC | 17635 |
| KEGG | hsa:29126 |
| Ensembl | ENSG00000120217 |
| String | 9606.ENSP00000370989 |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Specificity | The mouse monoclonal antibody recognizes CD274 / PD-L1 (also known as B7-H1), a 40 kDa type I transmembrane protein expressed by dendritic cells, activated T cells, activated monocytes, and in various tissues, above all in heart and skeletal muscle, placenta and lung, and in many cancer cells, including T cell lymphomas, melanomas, and glioblastomas. |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |