CD2 Antigen Cytoplasmic Tail-Binding Protein 2 (CD2BP2) Antibody

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Target	CD2 Antigen Cytoplasmic Tail-Binding Protein 2 (CD2BP2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human CD2BP2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95400 (UniProt, ExPASy)
UniProt Secondary AC	B2RDX2, Q9ULP2
UniProt Entry Name	CD2B2_HUMAN
Gene Symbol	CD2BP2
KEGG	hsa:10421
String	9606.ENSP00000304903
Molecular Weight	Calculated MW: 37.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse CD2BP2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on CD2 Antigen Cytoplasmic Tail-Binding Protein 2 (CD2BP2)

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