Tumor Necrosis Factor Receptor Superfamily Member 8 / CD30 (TNFRSF8) Antibody
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Catalogue No: abx011832
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF- kappa B. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 8 / CD30 (TNFRSF8)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 8 / CD30 (TNFRSF8) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Apoptosis, Tumor Immunity, Reproductive Science, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD30 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P28908 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AN79, B9EGD9, D3YTD8, Q6P4D9 |
| UniProt Entry Name | TNR8_HUMAN |
| Gene Symbol | TNFRSF8 |
| GeneID | 943 |
| OMIM | 153243 |
| HGNC | 11923 |
| KEGG | hsa:943 |
| Ensembl | ENSG00000120949 |
| String | 9606.ENSP00000263932 |
| Molecular Weight | 64 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |