Cluster of Differentiation 320 (CD320) Antibody
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Catalogue No: abx027232
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The CD320 antigen gene encodes the transcobalamin receptor (TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by receptors expressed on the cell surface. Transcobalamin II (TCN2; MIM 613441), a plasma protein secreted by endothelial cells, binds the cobalamin absorbed in the distal ileum and carries 10 to 30% of total circulating cobalamin. CD320 encodes a transcobalamin receptor that binds TCN2-cobalamin at the plasma membrane and internalizes the complex by endocytosis (Quadros et al., 2009 [PubMed 18779389]).
Research Articles on Cluster of Differentiation 320 (CD320)
| Target | Cluster of Differentiation 320 (CD320) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Immunology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 153-182 amino acids from the C-terminal region of human CD320. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9NPF0 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RDS5, D6W668, F5H6D3, Q53HF7 |
| UniProt Entry Name | CD320_HUMAN |
| Gene Symbol | CD320 |
| String | 9606.ENSP00000301458 |
| Molecular Weight | Calculated MW: 29 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |