Myeloid Cell Surface Antigen CD33 (CD33) Antibody

CD33 Antibody is a Rabbit Polyclonal antibody against CD33. CD33 is a type I transmembrane glycoprotein that is found on granulocyte and macrophage precursors in the bone marrow, but is absent from pluripotent stem cells. CD33 is also expressed on monocytes in peripheral blood. It is used as a marker to distinguish myelogenous leukemia cells from lymphoid or erythroid leukemias. CD33 may function as a sialic acid-dependent cell adhesion molecule.

Target	Myeloid Cell Surface Antigen CD33 (CD33)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 49-259 of human SIGLEC3/CD33.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P20138 (UniProt, ExPASy)
UniProt Secondary AC	B4E3P8, C9JEN7, F8WAL2, Q8TD24
UniProt Entry Name	CD33_HUMAN
Gene Symbol	CD33
GeneID	945
NCBI Accession	NP_001763.3
KEGG	hsa:945
String	9606.ENSP00000262262
Molecular Weight	Calculated MW: 40 kDa Observed MW: 70 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Myeloid Cell Surface Antigen CD33 (CD33)

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