Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

CD34 is a transmembrane glycoprotein with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells, endothelial cells and some fibroblasts. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells. CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.

Target	Hematopoietic Progenitor Cell Antigen CD34 (CD34)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of CD34 expressed in E. Coli.
Isotype	IgG
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P28906 (UniProt, ExPASy)
UniProt Secondary AC	A8K664, Q15970, Q15971, Q5JTA3, Q5JTA4, Q9UJB1
UniProt Entry Name	CD34_HUMAN
Gene Symbol	CD34
GeneID	947
OMIM	142230
HGNC	1662
KEGG	hsa:947
Ensembl	ENSG00000174059
String	9606.ENSP00000310036
Molecular Weight	41 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hematopoietic Progenitor Cell Antigen CD34 (CD34)

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