Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody
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Catalogue No: abx010523
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US$427.75
(Size: 100 µl)
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Datasheet SDS
CD34 is a transmembrane glycoprotein with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells, endothelial cells and some fibroblasts. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells. CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.
Research Articles on Hematopoietic Progenitor Cell Antigen CD34 (CD34)
| Target | Hematopoietic Progenitor Cell Antigen CD34 (CD34) |
| Research Area | Cellular Differentiation and Adhesion, Developmental Science, Genetics |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of CD34 expressed in E. Coli. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P28906 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K664, Q15970, Q15971, Q5JTA3, Q5JTA4, Q9UJB1 |
| UniProt Entry Name | CD34_HUMAN |
| Gene Symbol | CD34 |
| GeneID | 947 |
| OMIM | 142230 |
| HGNC | 1662 |
| KEGG | hsa:947 |
| Ensembl | ENSG00000174059 |
| String | 9606.ENSP00000310036 |
| Molecular Weight | 41 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |