T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3 gamma, delta and - zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11.

Target	T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of CD3E expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P07766 (UniProt, ExPASy)
UniProt Secondary AC	A8K997
UniProt Entry Name	CD3E_HUMAN
Gene Symbol	CD3E
GeneID	916
OMIM	186830
HGNC	1674
KEGG	hsa:916
Ensembl	ENSG00000198851
String	9606.ENSP00000354566
Molecular Weight	23 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)

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