T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody

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Catalogue No: abx027444
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, delta and zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Target T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human CD3E.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07766 (UniProt, ExPASy)
UniProt Secondary AC A8K997
UniProt Entry Name CD3E_HUMAN
KEGG hsa:916
String 9606.ENSP00000354566
Molecular Weight Calculated MW: 23.1 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Monkey CD3E.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)


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