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T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody

Catalogue No: abx001457
Price: £120.00
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T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody

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CD3E Antibody is a Rabbit Polyclonal antibody against CD3E. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Target T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CD3E.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07766 (UniProt, ExPASy)
UniProt Secondary AC A8K997
UniProt Entry Name CD3E_HUMAN
Gene Symbol CD3E
GeneID 916
KEGG hsa:916
String 9606.ENSP00000354566
Molecular Weight Calculated MW: 23 kDa
Observed MW: 23 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody

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