T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody
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Catalogue No: abx001457
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US$348.00
(Size: 60 µl)
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Datasheet SDS
CD3E Antibody is a Rabbit Polyclonal antibody against CD3E. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Research Articles on T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)
| Target | T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) |
| Research Area | Immunology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CD3E |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P07766 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K997 |
| UniProt Entry Name | CD3E_HUMAN |
| Gene Symbol | CD3E |
| GeneID | 916 |
| NCBI Accession | NP_000724.1 |
| KEGG | hsa:916 |
| String | 9606.ENSP00000354566 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
