T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G) Antibody

CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, delta and zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in the CD3G gene are associated with T cell immunodeficiency.

Target	T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human CD3G.
Isotype	IgG
Form	Liquid
Purification	Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS, then purified by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P09693 (UniProt, ExPASy)
UniProt Secondary AC	Q2HIZ6
UniProt Entry Name	CD3G_HUMAN
NCBI Accession	NP_000064.1
KEGG	hsa:917
String	9606.ENSP00000431445
Molecular Weight	Calculated MW: 20.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G)

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