T-Cell Surface Glycoprotein CD4 (CD4) Antibody

CD4 Antibody is a Rabbit Polyclonal antibody against CD4. This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Target	T-Cell Surface Glycoprotein CD4 (CD4)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 26-317 of human CD4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01730 (UniProt, ExPASy)
UniProt Secondary AC	B2R737, D3DUS5, Q4ZGK2, Q5U066, Q9UDE5
UniProt Entry Name	CD4_HUMAN
Gene Symbol	CD4
GeneID	920
NCBI Accession	NP_000607.1
KEGG	hsa:920
String	9606.ENSP00000011653
Molecular Weight	Calculated MW: 51 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on T-Cell Surface Glycoprotein CD4 (CD4)

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