Membrane Cofactor Protein (CD46) Antibody

Catalogue No: abx001390
Price: £120.00
(Size: 20 µl)
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CD46 Antibody is a Rabbit Polyclonal antibody against CD46. CD46 is a type I membrane protein and a regulatory part of the complement system. This protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, CD46 can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, this protein may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 is found in a cluster on chromosome 1q32 with other proteins that are structural components of the complement system. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.

Target Membrane Cofactor Protein (CD46)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CD46.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P15529 (UniProt, ExPASy)
UniProt Entry Name MCP_HUMAN
Gene Symbol CD46
GeneID 4179
KEGG hsa:4179
String 9606.ENSP00000313875
Molecular Weight Calculated MW: 36 kDa, 39 kDa, 40 kDa, 41 kDa, 42 kDa, 43 kDa, 44 kDa
Observed MW: 50-56 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Membrane Cofactor Protein (CD46)

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