CD59 Glycoprotein (CD59) Antibody
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Catalogue No: abx011952
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation.
Research Articles on CD59 Glycoprotein (CD59)
| Target | CD59 Glycoprotein (CD59) |
| Research Area | Apoptosis, Tumor Immunity, Immunology, Neuroscience, Developmental Science, Pulmonology, Autoimmunity, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/50 - 1/200, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD59 (AA: 31-111) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P13987 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PR17 |
| Gene Symbol | CD59 |
| GeneID | 966 |
| OMIM | 107271 |
| HGNC | 1689 |
| Ensembl | ENSG00000085063 |
| Molecular Weight | 14.2 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |