CD59 Glycoprotein (CD59) Antibody (HRP)

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Catalogue No: abx108081
Price: US$188.50
(Size: 20 µg)

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Datasheet SDS
CD59 Glycoprotein Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP against CD59 Glycoprotein. CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex (MAC), whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This inhibitor appears to be species-specific. This protein also plays a role in signal transduction for T-cell activation complexed to a protein tyrosine kinase. CD59 deficiency results in hemolytic anemia and thrombosis, which can lead to cerebral infarction.

Target CD59 Glycoprotein (CD59)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA
Host Rabbit
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Conjugation HRP
Immunogen Recombinant human CD59 glycoprotein (26-102AA).
Isotype IgG
Form Liquid
Purity > 95%
Purification Purified by Protein G.
Storage Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P13987 (UniProt, ExPASy)
UniProt Secondary AC E9PR17
Gene Symbol CD59
GeneID 966
OMIM 107271
Buffer 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on CD59 Glycoprotein (CD59)


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