CD70 Antigen / TNFSF7 (CD70) Antibody

CD70 Antibody is a Rabbit Polyclonal antibody against CD70. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008].

Target	CD70 Antigen / TNFSF7 (CD70)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 47-126 of human CD70.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P32970 (UniProt, ExPASy)
UniProt Secondary AC	B4DPR8, Q53XX4, Q96J57
UniProt Entry Name	CD70_HUMAN
Gene Symbol	CD70
GeneID	970
NCBI Accession	NP_001243.1
KEGG	hsa:970
String	9606.ENSP00000245903
Molecular Weight	Calculated MW: 21 kDa Observed MW: 54 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on CD70 Antigen / TNFSF7 (CD70)

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