T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody

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Catalogue No: abx001112
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
CD86 Antibody is a Rabbit Polyclonal antibody against CD86. This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].

Target T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86)
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 25-133 of human CD86.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P42081 (UniProt, ExPASy)
UniProt Entry Name CD86_HUMAN
Gene Symbol CD86
GeneID 942
NCBI Accession NP_787058.4
KEGG hsa:942
String 9606.ENSP00000332049
Molecular Weight Calculated MW: 38 kDa
Observed MW: 60 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86)


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