T-Cell Surface Glycoprotein CD8 Alpha Chain (CD8A) Antibody

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Catalogue No: abx027833
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.

Target T-Cell Surface Glycoprotein CD8 Alpha Chain (CD8A)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 59-88 amino acids from the N-terminal region of human CD8A.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01732 (UniProt, ExPASy)
UniProt Secondary AC B4DT80, D6W5M8, Q13970, Q4ZG17
UniProt Entry Name CD8A_HUMAN
Gene Symbol CD8A
KEGG hsa:925
String 9606.ENSP00000386559
Molecular Weight Calculated MW: 25.7 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on T-Cell Surface Glycoprotein CD8 Alpha Chain (CD8A)


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