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T-Cell Surface Glycoprotein CD8 Beta Chain (CD8B) Antibody

Catalogue No: abx002335
Price: £120.00
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T-Cell Surface Glycoprotein CD8 Beta Chain (CD8B) Antibody

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CD8B Antibody is a Rabbit Polyclonal antibody against CD8B. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Target T-Cell Surface Glycoprotein CD8 Beta Chain (CD8B)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CD8B.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P10966 (UniProt, ExPASy)
Gene Symbol CD8B
GeneID 926
Molecular Weight Calculated MW: 20 kDa, 22 kDa, 23 kDa, 24 kDa, 25 kDa, 27 kDa
Observed MW: 45 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on T-Cell Surface Glycoprotein CD8 Beta Chain (CD8B) Antibody

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