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Cyclin-Dependent Kinase 1 (CDK1) Antibody
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Catalogue No: abx033448
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
CDK1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Research Articles on Cyclin-Dependent Kinase 1 (CDK1)
| Target | Cyclin-Dependent Kinase 1 (CDK1) |
| Research Area | Signal Transduction, Enzymes and Kinases, Tumor Immunity, Neuroscience, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human CDC2 (CDK1). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P06493 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7C4, C9J497, O60764 |
| UniProt Entry Name | CDK1_HUMAN |
| KEGG | hsa:983 |
| String | 9606.ENSP00000378699 |
| Molecular Weight | Calculated MW: 34.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow CDK1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |