Cell Division Cycle 25A (CDC25A) Antibody

CDC25A Antibody is a Rabbit Polyclonal antibody against CDC25A. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Target	Cell Division Cycle 25A (CDC25A)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 86-328 of CDC25A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30304 (UniProt, ExPASy)
UniProt Secondary AC	Q8IZH5, Q96IL3, Q9H2F2
UniProt Entry Name	MPIP1_HUMAN
Gene Symbol	CDC25A
GeneID	993
NCBI Accession	NP_001780.2
KEGG	hsa:993
String	9606.ENSP00000303706
Molecular Weight	Calculated MW: 59 kDa Observed MW: 70 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cell Division Cycle 25A (CDC25A)

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