Cell Division Cycle 45 (cdc45) Antibody
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Catalogue No: abx001664
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US$217.50
(Size: 20 µl)
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Datasheet SDS
cdc45 Antibody is a Rabbit Polyclonal antibody against cdc45. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
Research Articles on Cell Division Cycle 45 (cdc45)
| Target | Cell Division Cycle 45 (cdc45) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to cdc45. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O75419 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DDB4, B4DDU3, E9PDH7, O60856, Q20WK8, Q6UW54, Q9UP68 |
| UniProt Entry Name | CDC45_HUMAN |
| Gene Symbol | CDC45 |
| GeneID | 8318 |
| NCBI Accession | NP_003495.1 |
| KEGG | hsa:8318 |
| String | 9606.ENSP00000405726 |
| Molecular Weight | Calculated MW: 66 kDa Observed MW: 60 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
