Cell Division Cycle 45 (cdc45) Antibody

Catalogue No: abx001664
Price: £120.00
(Size: 20 µl)
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cdc45 Antibody is a Rabbit Polyclonal antibody against cdc45. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].

Target cdc45
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human cdc45.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O75419 (UniProt, ExPASy)
UniProt Secondary AC B4DDB4, B4DDU3, E9PDH7, O60856, Q20WK8, Q6UW54, Q9UP68
UniProt Entry Name CDC45_HUMAN
Gene Symbol CDC45
GeneID 8318
KEGG hsa:8318
String 9606.ENSP00000405726
Molecular Weight Calculated MW: 60 kDa, 65 kDa, 68 kDa
Observed MW: 60 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on cdc45

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