Parafibromin (CDC73) Antibody

CDC73 Antibody is a Rabbit Polyclonal antibody against CDC73. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009].

Target	Parafibromin (CDC73)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 435-505 of human HRPT2 / CDC73.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q6P1J9 (UniProt, ExPASy)
UniProt Secondary AC	A6NLZ8, B2RBR2, Q6PK51, Q96A07, Q9H245, Q9H5L7
UniProt Entry Name	CDC73_HUMAN
Gene Symbol	CDC73
GeneID	79577
KEGG	hsa:79577
String	9606.ENSP00000356405
Molecular Weight	Calculated MW: 61 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Parafibromin (CDC73)

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