Borealin (CDCA8) Antibody
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Catalogue No: abx028083
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US$326.25
(Size: 80 µl)
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Datasheet SDS
CDCA8 is a component of the chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The CPC complex, a key regulator of mitosis, has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 may be required to direct the CPC to centromeric DNA.
Research Articles on Borealin (CDCA8)
| Target | Borealin (CDCA8) |
| Research Area | Signaling Pathways |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 115-144 amino acids from the Central region of human CDCA8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q53HL2 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DPT4, Q53HN1, Q96AM3, Q9NVW5 |
| UniProt Entry Name | BOREA_HUMAN |
| NCBI Accession | NP_001243804.1 NP_060571.1 |
| KEGG | hsa:55143 |
| String | 9606.ENSP00000362146 |
| Molecular Weight | Calculated MW: 31.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |