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Cadherin-1 (CDH1) Antibody
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Catalogue No: abx034792
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Research Articles on Cadherin-1 (CDH1)
| Target | Cadherin-1 (CDH1) |
| Research Area | Tumour Immunity |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | WB: 1/4000, IHC-P: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified His-tagged CDH1 protein |
| Isotype | IgG1 Kappa |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12830 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K1U7, Q13799, Q14216, Q15855, Q16194, Q4PJ14, Q9UII8 |
| UniProt Entry Name | CADH1_HUMAN |
| NCBI Accession | NP_004351.1 |
| KEGG | hsa:999 |
| String | 9606.ENSP00000261769 |
| Molecular Weight | Calculated MW: 97.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |