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Cadherin 11 (CDH11) Antibody
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Catalogue No: abx030381
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Research Articles on Cadherin 11 (CDH11)
| Target | Cadherin 11 (CDH11) |
| Research Area | Cellular Differentiation and Adhesion, Tumor Immunity, Bone Metabolism, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 622-650 amino acids from the C-terminal region of human CDH11. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P55287 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K5D6, A8MZC8, B7WP28, Q15065, Q15066, Q9UQ93, Q9UQ94 |
| UniProt Entry Name | CAD11_HUMAN |
| KEGG | hsa:1009 |
| String | 9606.ENSP00000268603 |
| Molecular Weight | Calculated MW: 88 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |