Cadherin-13 (CDH13) Antibody
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Catalogue No: abx001461
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US$348.00
(Size: 60 µl)
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Datasheet SDS
CDH13 Antibody is a Rabbit Polyclonal antibody against CDH13. This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011].
Research Articles on Cadherin-13 (CDH13)
| Target | Cadherin-13 (CDH13) |
| Research Area | Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Cardiovascular Biology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human Cadherin-13 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P55290 (UniProt, ExPASy) |
| UniProt Secondary AC | A8W476, A8W477, B7Z590, C9JRI6, J3KN62, Q6GTW4, Q8TBX3 |
| UniProt Entry Name | CAD13_HUMAN |
| Gene Symbol | CDH13 |
| GeneID | 1012 |
| OMIM | 601364 |
| NCBI Accession | NP_001248.1 |
| HGNC | 1753 |
| KEGG | hsa:1012 |
| String | 9606.ENSP00000268613 |
| Molecular Weight | Calculated MW: 19 kDa/21 kDa/73 kDa/78 kDa/83 kDa Observed MW: 70 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-7 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
