Cadherin, Neuronal (CDH2) Antibody

CDH2 Antibody is a Rabbit Polyclonal antibody against CDH2. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Target	Cadherin, Neuronal (CDH2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 488-587 of human N-Cadherin.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P19022 (UniProt, ExPASy)
UniProt Secondary AC	A8MWK3, B0YIY6, Q14923, Q8N173
UniProt Entry Name	CADH2_HUMAN
Gene Symbol	CDH2
GeneID	1000
NCBI Accession	NP_001783.2
KEGG	hsa:1000
String	9606.ENSP00000269141
Molecular Weight	Calculated MW: 100 kDa Observed MW: 80/135 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cadherin, Neuronal (CDH2)

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