Cadherin 20 (CDH20) Antibody

This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

Target	Cadherin 20 (CDH20)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 111-140 amino acids from the N-terminal region of human CDH20.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9HBT6 (UniProt, ExPASy)
UniProt Secondary AC	Q495S3
UniProt Entry Name	CAD20_HUMAN
Gene Symbol	CDH20
String	9606.ENSP00000262717
Molecular Weight	Calculated MW: 89 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat CDH20.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cadherin 20 (CDH20)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue