CDK2 (pT160) Antibody

CDK2 (pT160) Antibody is a Rabbit Polyclonal antibody against CDK2 (pT160). The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Target	CDK2 (pT160)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around T160 of human CDK2 (NP_001789.2?/NP_001249.1).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P24941 (UniProt, ExPASy)
UniProt Secondary AC	A8K7C6, O75100
UniProt Entry Name	CDK2_HUMAN
Gene Symbol	CDK2
GeneID	1017
NCBI Accession	NP_001789.2 NP_001249.1
KEGG	hsa:1017
String	9606.ENSP00000266970
Molecular Weight	Calculated MW: 34 kDa Observed MW: 32 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on CDK2 (pT160)

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