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Cyclin-Dependent Kinase 4 (CDK4) Antibody

Catalogue No: abx000696
Price: £95.00
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Cyclin-Dependent Kinase 4 (CDK4) Antibody Cyclin-Dependent Kinase 4 (CDK4) Antibody Cyclin-Dependent Kinase 4 (CDK4) Antibody Cyclin-Dependent Kinase 4 (CDK4) Antibody Cyclin-Dependent Kinase 4 (CDK4) Antibody Cyclin-Dependent Kinase 4 (CDK4) Antibody Cyclin-Dependent Kinase 4 (CDK4) Antibody Cyclin-Dependent Kinase 4 (CDK4) Antibody Cyclin-Dependent Kinase 4 (CDK4) Antibody

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CDK4 Antibody is a Rabbit Polyclonal antibody against CDK4. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

Target CDK4
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC, IF/ICC
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein. Center-peptide of human CDK4.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 20 kDa, 33 kDa
Observed MW: 32 kDa
Swiss Prot P11802
GeneID 1019
Gene Symbol CDK4
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cyclin-Dependent Kinase 4 (CDK4) Antibody

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