Cyclin-Dependent Kinase 9 (CDK9) Antibody

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family.CDK family members are highly similar to the gene products of S.cerevisiae cdc28, and S.pombe cdc2, and known as important cell cycle regulators.This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II.This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K.HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.

Target	Cyclin-Dependent Kinase 9 (CDK9)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CDK9 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P50750 (UniProt, ExPASy)
UniProt Secondary AC	Q5JU24, Q5JU25, Q5U006, Q96TF1
UniProt Entry Name	CDK9_HUMAN
Gene Symbol	CDK9
GeneID	1025
OMIM	603251
HGNC	1780
KEGG	hsa:1025
Ensembl	ENSG00000136807
String	9606.ENSP00000362361
Molecular Weight	43 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cyclin-Dependent Kinase 9 (CDK9)

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