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Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody

Catalogue No: abx000672
Price: £120.00
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Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody

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CDKN1B Antibody is a Rabbit Polyclonal antibody against CDKN1B. This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).

Target CDKN1B
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications IHC, IF/ICC
Host Rabbit
Recommended dilutions IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human CDKN1B.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P46527 (UniProt, ExPASy)
UniProt Secondary AC Q16307, Q5U0H2, Q9BUS6
UniProt Entry Name CDN1B_HUMAN
Gene Symbol CDKN1B
GeneID 1027
KEGG hsa:1027
String 9606.ENSP00000228872
Molecular Weight Calculated MW: 22 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody

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