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Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody

Catalogue No: abx000672
Price: £95.00
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Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody

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CDKN1B Antibody is a Rabbit Polyclonal antibody against CDKN1B. This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).

Target CDKN1B
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Tested Applications IHC, IF/ICC
Recommended dilutions IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant fusion protein of human CDKN1B.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 22 kDa
Swiss Prot P46527
GeneID 1027
Gene Symbol CDKN1B
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody

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