Cyclin-Dependent Kinase Inhibitor 2A (CDKN2A) Antibody

This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants.

Target	Cyclin-Dependent Kinase Inhibitor 2A (CDKN2A)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CDKN2A (AA: 1-156) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P42771 (UniProt, ExPASy)
UniProt Entry Name	CDN2A_HUMAN
Gene Symbol	CDKN2A
GeneID	1029
OMIM	600160 155601
HGNC	1787
KEGG	hsa:1029
Ensembl	ENSG00000147889
String	9606.ENSP00000418915
Molecular Weight	16.5 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cyclin-Dependent Kinase Inhibitor 2A (CDKN2A)

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