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Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Antibody

Catalogue No: abx001427
Price: £120.00
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Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Antibody

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CEACAM1 Antibody is a Rabbit Polyclonal antibody against CEACAM1. This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Target Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CEACAM1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P13688 (UniProt, ExPASy)
UniProt Entry Name CEAM1_HUMAN
Gene Symbol CEACAM1
GeneID 634
KEGG hsa:634
String 9606.ENSP00000161559
Molecular Weight Calculated MW: 27 kDa, 35-57 kDa
Observed MW: 58 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Antibody

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