Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) Antibody

This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Target	Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human CEACAM3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P40198 (UniProt, ExPASy)
UniProt Secondary AC	G5E978, Q3KPH9
UniProt Entry Name	CEAM3_HUMAN
Gene Symbol	CEACAM3
KEGG	hsa:1084
String	9606.ENSP00000349971
Molecular Weight	Calculated MW: 27.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3)

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