Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) Antibody
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Catalogue No: abx027645
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Research Articles on Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3)
| Target | Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) |
| Research Area | Cellular Differentiation and Adhesion |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human CEACAM3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P40198 (UniProt, ExPASy) |
| UniProt Secondary AC | G5E978, Q3KPH9 |
| UniProt Entry Name | CEAM3_HUMAN |
| Gene Symbol | CEACAM3 |
| KEGG | hsa:1084 |
| String | 9606.ENSP00000349971 |
| Molecular Weight | Calculated MW: 27.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |