CCAAT/Enhancer Binding Protein Beta (CEBPB) Antibody

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP alpha, CEBP delta, and CEBP gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.

Target	CCAAT/Enhancer Binding Protein Beta (CEBPB)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CEBPB expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P17676 (UniProt, ExPASy)
UniProt Secondary AC	A8K671, Q96IH2, Q9H4Z5
UniProt Entry Name	CEBPB_HUMAN
Gene Symbol	CEBPB
GeneID	1051
OMIM	189965
HGNC	1834
KEGG	hsa:1051
Ensembl	ENSG00000172216
String	9606.ENSP00000305422
Molecular Weight	36 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on CCAAT/Enhancer Binding Protein Beta (CEBPB)

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