Chymotrypsin Like Elastase Family Member 3B (CELA3B) Antibody
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Catalogue No: abx027596
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Chymotrypsin Like Elastase Family Member 3B (CELA3B) Antibody is a rabbit polyclonal antibody for CELA3B. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
Research Articles on Chymotrypsin Like Elastase Family Member 3B (CELA3B)
| Target | Chymotrypsin Like Elastase Family Member 3B (CELA3B) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human CELA3B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P08861 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RE44, P11423, Q5VU28, Q5VU29, Q5VU30 |
| UniProt Entry Name | CEL3B_HUMAN |
| Gene Symbol | CELA3B |
| KEGG | hsa:23436 |
| String | 9606.ENSP00000338369 |
| Molecular Weight | Calculated MW: 29.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |