Cocaine Esterase (CES2) Antibody

CES2 Antibody is a Rabbit Polyclonal antibody against CES2. This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010].

Target	Cocaine Esterase (CES2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 310-410 of human CES2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00748 (UniProt, ExPASy)
UniProt Secondary AC	A0A024R6X1, A8K367, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8
UniProt Entry Name	EST2_HUMAN
Gene Symbol	CES2
GeneID	8824
NCBI Accession	NP_003860.3
KEGG	hsa:8824
String	9606.ENSP00000317842
Molecular Weight	Calculated MW: 62 kDa Observed MW: 67 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cocaine Esterase (CES2)

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