Choline O-Acetyltransferase (CHAT) Antibody

Catalogue No: abx001939
Price: £120.00
(Size: 20 µl)
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Choline O-Acetyltransferase (CHAT) Antibody Choline O-Acetyltransferase (CHAT) Antibody

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CHAT Antibody is a Rabbit Polyclonal antibody against CHAT. This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

Target CHAT
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CHAT.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P28329 (UniProt, ExPASy)
UniProt Secondary AC A2BDF4, A2BDF5, Q16488, Q9BQ23, Q9BQ35, Q9BQE1
UniProt Entry Name CLAT_HUMAN
Gene Symbol CHAT
GeneID 1103
KEGG hsa:1103
String 9606.ENSP00000337103
Molecular Weight Calculated MW: 70 kDa, 74 kDa, 82 kDa
Observed MW: 68 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Choline O-Acetyltransferase (CHAT) Antibody

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