Choline O-Acetyltransferase (CHAT) Antibody

CHAT Antibody is a Rabbit Polyclonal antibody against CHAT. This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

Target	Choline O-Acetyltransferase (CHAT)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CHAT.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P28329 (UniProt, ExPASy)
UniProt Secondary AC	A2BDF4, A2BDF5, Q16488, Q9BQ23, Q9BQ35, Q9BQE1
UniProt Entry Name	CLAT_HUMAN
Gene Symbol	CHAT
GeneID	1103
NCBI Accession	NP_065574.4
KEGG	hsa:1103
String	9606.ENSP00000337103
Molecular Weight	Calculated MW: 83 kDa Observed MW: 71 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Choline O-Acetyltransferase (CHAT)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue