Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody
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Catalogue No: abx147377
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US$420.50
(Size: 100 µg)
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Datasheet SDS
Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody is a Rabbit Polyclonal antibody for the detection of CXCR3. This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
Research Articles on Chemokine C-X-C-Motif Receptor 3 (CXCR3)
| Target | Chemokine C-X-C-Motif Receptor 3 (CXCR3) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Immunology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | CXCR3 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P49682 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R982, O15185, Q7Z710, Q9P2T4, Q9P2T5 |
| UniProt Entry Name | CXCR3_HUMAN |
| Gene Symbol | CXCR3 |
| GeneID | 2833 |
| OMIM | 300574 |
| HGNC | 4540 |
| KEGG | hsa:2833 |
| Ensembl | ENSG00000186810 |
| String | 9606.ENSP00000362795 |
| Molecular Weight | Observed MW: 45 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |