Chromogranin A (CHGA) Antibody

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins.It is found in secretory vesicles of neurons and endocrine cells.This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin.These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system.Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein.However, biological activities for these molecules have not been shown.

Target	Chromogranin A (CHGA)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IF/ICC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/50, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CHGA (87-252 AA) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P10645 (UniProt, ExPASy)
UniProt Secondary AC	B2R9E9, Q53FA8, Q6NR84, Q96E84, Q96GL7, Q9BQB5
UniProt Entry Name	CMGA_HUMAN
Gene Symbol	CHGA
GeneID	1113
OMIM	118910
HGNC	1929
KEGG	hsa:1113
Ensembl	ENSG00000100604
String	9606.ENSP00000216492
Molecular Weight	50.7 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chromogranin A (CHGA)

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